Biophysics of filament length regulation by molecular motors
نویسندگان
چکیده
منابع مشابه
Biophysics of filament length regulation by molecular motors.
Regulating physical size is an essential problem that biological organisms must solve from the subcellular to the organismal scales, but it is not well understood what physical principles and mechanisms organisms use to sense and regulate their size. Any biophysical size-regulation scheme operates in a noisy environment and must be robust to other cellular dynamics and fluctuations. This work d...
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Length regulation of microtubules (MTs) is essential for many cellular processes. Molecular motors like kinesin-8, which move along MTs and also act as depolymerases, are known as key players in MT dynamics. However, the regulatory mechanisms of length control remain elusive. Here, we investigate a stochastic model accounting for the interplay between polymerization kinetics and motor-induced d...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2013
ISSN: 1478-3967,1478-3975
DOI: 10.1088/1478-3975/10/3/036004